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1.

Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.

Toda, Gotaro; Soeda, Kotaro; Okazaki, Yukiko; Kobayashi, Naoki; Masuda, Yukari; Arakawa, Naoko; Suwanai, Hirotsugu; Masamoto, Yosuke; Izumida, Yoshihiko; Kamei, Nozomu; Sasako, Takayoshi; Suzuki, Ryo; Kubota, Tetsuya; Kubota, Naoto; Kurokawa, Mineo; Tobe, Kazuyuki; Noda, Tetsuo; Honda, Kenya; Accili, Domenico; Yamauchi, Toshimasa; Kadowaki, Takashi; Ueki, Kohjiro.

Mol Cell ; 79(1): 43-53.e4, 2020 07 02.

Artículo en Inglés | MEDLINE | ID: mdl-32464093

2.

Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor.

Hosoi, Tatsuya; Yakabe, Mitsutaka; Sasakawa, Hiroko; Sasako, Takayoshi; Ueki, Kohjiro; Kato, Shigeaki; Tokuoka, Suzumi M; Oda, Yoshiya; Abe, Masahiro; Matsumoto, Toshio; Akishita, Masahiro; Ogawa, Sumito.

Proc Natl Acad Sci U S A ; 120(4): e2218032120, 2023 Jan 24.

Artículo en Inglés | MEDLINE | ID: mdl-36669097

3.

Addressing screams for evidence on renoprotection by GLP-1 receptor agonists.

Sasako, Takayoshi; Yamauchi, Toshimasa.

Kidney Int ; 101(2): 222-224, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35065690

4.

Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes.

Ueki, Kohjiro; Sasako, Takayoshi; Okazaki, Yukiko; Miyake, Kana; Nangaku, Masaomi; Ohashi, Yasuo; Noda, Mitsuhiko; Kadowaki, Takashi.

Kidney Int ; 99(1): 256-266, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32891604

5.

[Aging-related frailty and sarcopenia. Frailty/sarcopenia and insulin/IGF-1 signaling.]

Sasako, Takayoshi; Ueki, Kohjiro.

Clin Calcium ; 28(9): 1221-1228, 2018.

Artículo en Japonés | MEDLINE | ID: mdl-30146508

6.

[Homeostasis and Disorder of Musculoskeletal System.Roles of the motor system in systemic metabolism and the aging-related disorders.]

Sasako, Takayoshi; Ueki, Kohjiro.

Clin Calcium ; 28(3): 373-379, 2018.

Artículo en Japonés | MEDLINE | ID: mdl-29512529

7.

Insulin/IGF-1 signaling and aging.

Sasako, Takayoshi; Ueki, Kohjiro.

Nihon Rinsho ; 74(9): 1435-1440, 2016 Sep.

Artículo en Japonés | MEDLINE | ID: mdl-30557473

8.

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.

Kobayashi, Naoki; Ueki, Kohjiro; Okazaki, Yukiko; Iwane, Aya; Kubota, Naoto; Ohsugi, Mitsuru; Awazawa, Motoharu; Kobayashi, Masatoshi; Sasako, Takayoshi; Kaneko, Kazuma; Suzuki, Miho; Nishikawa, Yoshitaka; Hara, Kazuo; Yoshimura, Kotaro; Koshima, Isao; Goyama, Susumu; Murakami, Koji; Sasaki, Junko; Nagai, Ryozo; Kurokawa, Mineo; Sasaki, Takehiko; Kadowaki, Takashi.

Proc Natl Acad Sci U S A ; 108(14): 5753-8, 2011 Apr 05.

Artículo en Inglés | MEDLINE | ID: mdl-21436039

9.

Exploring mechanisms underlying diabetes comorbidities and strategies to prevent vascular complications.

Sasako, Takayoshi.

Diabetol Int ; 15(1): 34-40, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-38264227

10.

The influence of trinucleotide repeats in the androgen receptor gene on androgen-related traits and diseases.

Sasako, Takayoshi; Ilboudo, Yann; Liang, Kevin Y H; Chen, Yiheng; Yoshiji, Satoshi; Richards, J Brent.

J Clin Endocrinol Metab ; 2024 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-38701087

11.

Corticosteroid-triggered acute skeletal muscle loss in lipodystrophy: A case report.

Sasako, Takayoshi; Suzuki, Ken; Odawara, Sara; Suwanai, Hirotsugu; Akuta, Naoko; Kubota, Naoto; Ueki, Kohjiro; Kadowaki, Takashi; Yamauchi, Toshimasa.

J Diabetes Investig ; 2024 Feb 19.

Artículo en Inglés | MEDLINE | ID: mdl-38372649

12.

Overexpression of UBE2E2 in Mouse Pancreatic ß-Cells Leads to Glucose Intolerance via Reduction of ß-Cell Mass.

Sakurai, Yoshitaka; Kubota, Naoto; Takamoto, Iseki; Wada, Nobuhiro; Aihara, Masakazu; Hayashi, Takanori; Kubota, Tetsuya; Hiraike, Yuta; Sasako, Takayoshi; Nakao, Harumi; Aiba, Atsu; Chikaoka, Yoko; Kawamura, Takeshi; Kadowaki, Takashi; Yamauchi, Toshimasa.

Diabetes ; 73(3): 474-489, 2024 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-38064504

13.

Sarcopenia: Loss of mighty armor against frailty and aging.

Sasako, Takayoshi; Ueki, Kohjiro.

J Diabetes Investig ; 14(10): 1145-1147, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37551792

14.

Intensified Multifactorial Intervention in Patients with Type 2 Diabetes Mellitus.

Sasako, Takayoshi; Yamauchi, Toshimasa; Ueki, Kohjiro.

Diabetes Metab J ; 47(2): 185-197, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36631991

15.

Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.

Soeda, Kotaro; Sasako, Takayoshi; Enooku, Kenichiro; Kubota, Naoto; Kobayashi, Naoki; Ikushima, Yoshiko Matsumoto; Awazawa, Motoharu; Bouchi, Ryotaro; Toda, Gotaro; Yamada, Tomoharu; Nakatsuka, Takuma; Tateishi, Ryosuke; Kakiuchi, Miwako; Yamamoto, Shogo; Tatsuno, Kenji; Atarashi, Koji; Suda, Wataru; Honda, Kenya; Aburatani, Hiroyuki; Yamauchi, Toshimasa; Fujishiro, Mitsuhiro; Noda, Tetsuo; Koike, Kazuhiko; Kadowaki, Takashi; Ueki, Kohjiro.

Nat Commun ; 14(1): 6584, 2023 10 18.

Artículo en Inglés | MEDLINE | ID: mdl-37852976

16.

Severe aortic stenosis during leptin replacement therapy in a patient with generalized lipodystrophy-associated progeroid syndrome due to an LMNA variant: A case report.

Sasako, Takayoshi; Kadowaki, Hiroko; Fujiwara, Takayuki; Kodera, Satoshi; Komuro, Issei; Kadowaki, Takashi; Yamauchi, Toshimasa.

J Diabetes Investig ; 13(9): 1636-1638, 2022 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-35524481

17.

Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.

Sasako, Takayoshi; Umehara, Toshihiro; Soeda, Kotaro; Kaneko, Kazuma; Suzuki, Miho; Kobayashi, Naoki; Okazaki, Yukiko; Tamura-Nakano, Miwa; Chiba, Tomoki; Accili, Domenico; Kahn, C Ronald; Noda, Tetsuo; Asahara, Hiroshi; Yamauchi, Toshimasa; Kadowaki, Takashi; Ueki, Kohjiro.

Nat Commun ; 13(1): 5655, 2022 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-36198696

18.

Asymptomatic myocardial infarction in a patient with myotonic dystrophy type 1.

Seki, Yuka; Yamada, Takanobu; Kiyosue, Arihiro; Kimura, Koichi; Uehara, Masae; Hatano, Masaru; Sasako, Takayoshi; Shirota, Yuichiro; Sudo, Atsushi; Ishiura, Hiroyuki; Toda, Tatsushi; Yamauchi, Toshimasa; Komuro, Issei.

J Cardiol Cases ; 26(4): 248-251, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-36187313

19.

Skeletal muscle mitoribosomal defects are linked to low bone mass caused by bone marrow inflammation in male mice.

Tian, Jingwen; Chung, Hyo Kyun; Moon, Ji Sun; Nga, Ha Thi; Lee, Ho Yeop; Kim, Jung Tae; Chang, Joon Young; Kang, Seul Gi; Ryu, Dongryeol; Che, Xiangguo; Choi, Je-Yong; Tsukasaki, Masayuki; Sasako, Takayoshi; Lee, Sang-Hee; Shong, Minho; Yi, Hyon-Seung.

J Cachexia Sarcopenia Muscle ; 13(3): 1785-1799, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35306755

20.

Generation of transgenic mice on an NOD/SCID background using the conventional microinjection technique.

Kumagai, Katsuyoshi; Kubota, Naoto; Saito, Toshiki I; Sasako, Takayoshi; Takizawa, Rumi; Sudo, Katsuko; Kurokawa, Mineo; Kadowaki, Takashi.

Biol Reprod ; 84(4): 682-8, 2011 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-21148106

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Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.

Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor.

Addressing screams for evidence on renoprotection by GLP-1 receptor agonists.

Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes.

[Aging-related frailty and sarcopenia. Frailty/sarcopenia and insulin/IGF-1 signaling.]

[Homeostasis and Disorder of Musculoskeletal System.Roles of the motor system in systemic metabolism and the aging-related disorders.]

Insulin/IGF-1 signaling and aging.

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.

Exploring mechanisms underlying diabetes comorbidities and strategies to prevent vascular complications.

The influence of trinucleotide repeats in the androgen receptor gene on androgen-related traits and diseases.

Corticosteroid-triggered acute skeletal muscle loss in lipodystrophy: A case report.

Overexpression of UBE2E2 in Mouse Pancreatic ß-Cells Leads to Glucose Intolerance via Reduction of ß-Cell Mass.

Sarcopenia: Loss of mighty armor against frailty and aging.

Intensified Multifactorial Intervention in Patients with Type 2 Diabetes Mellitus.

Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.

Severe aortic stenosis during leptin replacement therapy in a patient with generalized lipodystrophy-associated progeroid syndrome due to an LMNA variant: A case report.

Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.

Asymptomatic myocardial infarction in a patient with myotonic dystrophy type 1.

Skeletal muscle mitoribosomal defects are linked to low bone mass caused by bone marrow inflammation in male mice.

Generation of transgenic mice on an NOD/SCID background using the conventional microinjection technique.